CUPRIMINE vs TROXYCA ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. CUPRIMINE and TROXYCA ER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	TROXYCA ER
Rating	74/100	60/100
Pharmacy pays	—	~$36.74 /30
Type	RX	RX
Active ingredient	PENICILLAMINE	NALTREXONE HYDROCHLORIDE AND OXYCODONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Pfizer
Dosage forms	Capsule	Capsule, extended release
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	None
Half-life	—	about 3.5 to 4 hours
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine troxyca er

Rating

74/100

60/100

Pharmacy pays

—

~$36.74 /30

Type

Active ingredient

PENICILLAMINE

NALTREXONE HYDROCHLORIDE AND OXYCODONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Pfizer

Dosage forms

Capsule

Capsule, extended release

Drug class

Antirheumatic Agent

—

Boxed warning

None

Half-life

—

about 3.5 to 4 hours

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

Which is better-rated, Cuprimine or Troxyca ER?

By our independent rating, Cuprimine scores higher — 3.7 vs 3.0 out of 5 for Troxyca ER. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cuprimine and Troxyca ER?

Cuprimine contains Penicillamine, while Troxyca ER contains Naltrexone Hydrochloride and Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.