CUPRIMINE vs ORTHO-NOVUM 1/50 21

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. CUPRIMINE and ORTHO-NOVUM 1/50 21 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	ORTHO-NOVUM 1/50 21
Rating	74/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLAMINE	MESTRANOL AND NORETHINDRONE
Manufacturer	Valeant Pharm Intl	Ortho Mcneil Pharm
Dosage forms	Capsule	Tablet
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	None
Half-life	—	about 8 hours
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine ortho-novum 1/50 21

Rating

74/100

New

Pharmacy pays

—

Type

Active ingredient

PENICILLAMINE

MESTRANOL AND NORETHINDRONE

Manufacturer

Valeant Pharm Intl

Ortho Mcneil Pharm

Dosage forms

Capsule

Tablet

Drug class

Antirheumatic Agent

—

Boxed warning

None

Half-life

—

about 8 hours

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

What is the difference between Cuprimine and Ortho-Novum 1/50 21?

Cuprimine contains Penicillamine, while Ortho-Novum 1/50 21 contains Mestranol and Norethindrone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.