CUPRIMINE vs KANUMA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. CUPRIMINE and KANUMA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	KANUMA
Rating	74/100	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLAMINE	SEBELIPASE ALFA
Manufacturer	Valeant Pharm Intl	Alexion Pharm
Dosage forms	Capsule	Injectable
Drug class	Antirheumatic Agent	Hydrolytic Lysosomal Cholesteryl Ester-Specific Enzyme
Boxed warning	Boxed warning	None
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine kanuma

Rating

74/100

70/100

Pharmacy pays

—

Type

Active ingredient

PENICILLAMINE

SEBELIPASE ALFA

Manufacturer

Valeant Pharm Intl

Alexion Pharm

Dosage forms

Capsule

Injectable

Drug class

Antirheumatic Agent

Hydrolytic Lysosomal Cholesteryl Ester-Specific Enzyme

Boxed warning

None

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

Which is better-rated, Cuprimine or Kanuma?

By our independent rating, Cuprimine scores higher — 3.7 vs 3.5 out of 5 for Kanuma. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cuprimine and Kanuma?

Cuprimine contains Penicillamine, while Kanuma contains Sebelipase Alfa — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.