CUPRIMINE vs HISTAFED
Independent side-by-side comparison.
Possible drug interaction. CUPRIMINE and HISTAFED are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.
Rating
74/100
New
Pharmacy pays
—
~$8.29 /30
Type
RX
RX
Active ingredient
PENICILLAMINE
PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE
Manufacturer
Dosage forms
Capsule
Syrup
Drug class
Antirheumatic Agent
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Boxed warning
None
Half-life
—
roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)
Treats
Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration
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Frequently asked questions
What is the difference between Cuprimine and Histafed?
Cuprimine contains Penicillamine, while Histafed contains Pseudoephedrine Hydrochloride and Triprolidine Hydrochloride — they have different active ingredients.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.