CUPRIMINE vs EXFORGE HCT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. CUPRIMINE and EXFORGE HCT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	EXFORGE HCT
Rating	74/100	70/100
Pharmacy pays	—	~$0.33 /30
Type	RX	RX
Active ingredient	PENICILLAMINE	AMLODIPINE BESYLATE AND HYDROCHLOROTHIAZIDE AND VALSARTAN
Manufacturer	Valeant Pharm Intl	Novartis
Dosage forms	Capsule	Tablet
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 6 to 15 hours (the label reports a range, not a single number)
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine exforge hct

Rating

74/100

70/100

Pharmacy pays

—

~$0.33 /30

Type

Active ingredient

PENICILLAMINE

AMLODIPINE BESYLATE AND HYDROCHLOROTHIAZIDE AND VALSARTAN

Manufacturer

Valeant Pharm Intl

Novartis

Dosage forms

Capsule

Tablet

Drug class

Antirheumatic Agent

—

Boxed warning

Half-life

—

about 6 to 15 hours (the label reports a range, not a single number)

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

Which is better-rated, Cuprimine or Exforge Hct?

By our independent rating, Cuprimine scores higher — 3.7 vs 3.5 out of 5 for Exforge Hct. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cuprimine and Exforge Hct?

Cuprimine contains Penicillamine, while Exforge Hct contains Amlodipine Besylate and Hydrochlorothiazide and Valsartan — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.