CUPRIMINE vs DUETACT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. CUPRIMINE and DUETACT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	DUETACT
Rating	74/100	New
Pharmacy pays	—	~$0.91 /30
Type	RX	RX
Active ingredient	PENICILLAMINE	GLIMEPIRIDE AND PIOGLITAZONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Takeda Pharms USA
Dosage forms	Capsule	Tablet
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 3 to 7 hours (parent drug)
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine duetact

Rating

74/100

New

Pharmacy pays

—

~$0.91 /30

Type

Active ingredient

PENICILLAMINE

GLIMEPIRIDE AND PIOGLITAZONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Takeda Pharms USA

Dosage forms

Capsule

Tablet

Drug class

Antirheumatic Agent

—

Boxed warning

Half-life

—

about 3 to 7 hours (parent drug)

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

What is the difference between Cuprimine and Duetact?

Cuprimine contains Penicillamine, while Duetact contains Glimepiride and Pioglitazone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.