CUPRIMINE vs DISOPHROL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. CUPRIMINE and DISOPHROL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	DISOPHROL
Rating	74/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLAMINE	DEXBROMPHENIRAMINE MALEATE AND PSEUDOEPHEDRINE SULFATE
Manufacturer	Valeant Pharm Intl	Schering
Dosage forms	Capsule	Tablet, Tablet, extended release
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	None
Half-life	—	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine disophrol

Rating

74/100

New

Pharmacy pays

—

Type

Active ingredient

PENICILLAMINE

DEXBROMPHENIRAMINE MALEATE AND PSEUDOEPHEDRINE SULFATE

Manufacturer

Valeant Pharm Intl

Schering

Dosage forms

Capsule

Tablet, Tablet, extended release

Drug class

Antirheumatic Agent

—

Boxed warning

None

Half-life

—

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

What is the difference between Cuprimine and Disophrol?

Cuprimine contains Penicillamine, while Disophrol contains Dexbrompheniramine Maleate and Pseudoephedrine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.