CUPRIMINE vs DEPEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Attribute	CUPRIMINE	DEPEN
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLAMINE	PENICILLAMINE
Manufacturer	Valeant Pharm Intl	Mylan Speciality LP
Dosage forms	Capsule	Tablet
Drug class	Antirheumatic Agent	Antirheumatic Agent
Boxed warning	Boxed warning	Boxed warning
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

cuprimine depen

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

PENICILLAMINE

Manufacturer

Valeant Pharm Intl

Mylan Speciality LP

Dosage forms

Capsule

Tablet

Drug class

Antirheumatic Agent

Boxed warning

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

What is the difference between Cuprimine and Depen?

Both Cuprimine and Depen share the active ingredient Penicillamine.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.