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CRINONE vs PROMETRIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Rating

70/100
New

Pharmacy pays

~$12.29 /30
~$12.29 /30

Type

RX
RX

Active ingredient

PROGESTERONE
PROGESTERONE

Dosage forms

Topical
Capsule

Drug class

Progesterone
Progesterone

Boxed warning

None
None

Treats

Amenorrhea, Endometrial Hyperplasia, Female Infertility
Amenorrhea, Endometrial Hyperplasia, Female Infertility

Frequently asked questions

Which is cheaper, Crinone or Prometrium?

Pharmacies pay about the same to acquire either one — roughly $12.29 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Crinone and Prometrium?

Both Crinone and Prometrium share the active ingredient Progesterone.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.