CRESTOR vs ZOCOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. CRESTOR and ZOCOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CRESTOR	ZOCOR
Rating	70/100	70/100
Pharmacy pays	~$1.37 /30	~$0.93 /30
Type	RX	RX
Active ingredient	ROSUVASTATIN CALCIUM	SIMVASTATIN
Manufacturer	Astrazeneca	Organon
Dosage forms	Tablet	Tablet
Drug class	Hmg-Coa Reductase Inhibitor	Hmg-Coa Reductase Inhibitor
Boxed warning	None	None
Half-life	about 19 hours	about 2 hours (short) in typical adults
Treats	Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias	Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

crestor zocor

Rating

70/100

Pharmacy pays

~$1.37 /30

~$0.93 /30

Type

Active ingredient

ROSUVASTATIN CALCIUM

SIMVASTATIN

Manufacturer

Astrazeneca

Organon

Dosage forms

Tablet

Drug class

Hmg-Coa Reductase Inhibitor

Boxed warning

None

Half-life

about 19 hours

about 2 hours (short) in typical adults

Treats

Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

Frequently asked questions

Which is better-rated, Crestor or Zocor?

Crestor and Zocor are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Crestor or Zocor?

Zocor costs pharmacies less to acquire — about $0.93 vs $1.37 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Crestor and Zocor?

Crestor contains Rosuvastatin Calcium, while Zocor contains Simvastatin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.