COTEMPLA XR-ODT vs DEXTROAMPHETAMINE SULFATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. COTEMPLA XR-ODT and DEXTROAMPHETAMINE SULFATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COTEMPLA XR-ODT	DEXTROAMPHETAMINE SULFATE
Rating	New	72/100
Pharmacy pays	~$18.94 /30	~$29.94 /30
Type	RX	RX
Active ingredient	METHYLPHENIDATE	DEXTROAMPHETAMINE SULFATE
Manufacturer	Neos Theraps Inc	Tris Pharma Inc
Dosage forms	Tablet, orally disintegrating	Capsule, extended release, Solution, Tablet
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	Boxed warning
Half-life	about 2.7 hours	—
Treats	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy	Attention Deficit Disorder with Hyperactivity, Narcolepsy

cotempla xr-odt dextroamphetamine sulfate

Rating

New

72/100

Pharmacy pays

~$18.94 /30

~$29.94 /30

Type

Active ingredient

METHYLPHENIDATE

DEXTROAMPHETAMINE SULFATE

Manufacturer

Neos Theraps Inc

Tris Pharma Inc

Dosage forms

Tablet, orally disintegrating

Capsule, extended release, Solution, Tablet

Drug class

Central Nervous System Stimulant

Boxed warning

Half-life

about 2.7 hours

—

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Attention Deficit Disorder with Hyperactivity, Narcolepsy

Frequently asked questions

Which is cheaper, Cotempla XR-ODT or Dextroamphetamine Sulfate?

Cotempla XR-ODT costs pharmacies less to acquire — about $18.94 vs $29.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cotempla XR-ODT and Dextroamphetamine Sulfate?

Cotempla XR-ODT contains Methylphenidate, while Dextroamphetamine Sulfate contains Dextroamphetamine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.