COSMEGEN vs OPDIVO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. COSMEGEN and OPDIVO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COSMEGEN	OPDIVO
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DACTINOMYCIN	NIVOLUMAB
Manufacturer	Recordati Rare	Bristol Myers Squibb
Dosage forms	Injectable	Injectable
Drug class	Actinomycin	Programmed Death Receptor-1 Blocking Antibody
Boxed warning	None	None
Treats	Choriocarcinoma, Melanoma, Wilms Tumor	Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

cosmegen opdivo

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

DACTINOMYCIN

NIVOLUMAB

Manufacturer

Recordati Rare

Bristol Myers Squibb

Dosage forms

Injectable

Drug class

Actinomycin

Programmed Death Receptor-1 Blocking Antibody

Boxed warning

None

Treats

Choriocarcinoma, Melanoma, Wilms Tumor

Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

Frequently asked questions

What is the difference between Cosmegen and Opdivo?

Cosmegen contains Dactinomycin, while Opdivo contains Nivolumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.