CORTRIL vs HYDROCORTONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	CORTRIL	HYDROCORTONE
Rating	64/100	70/100
Pharmacy pays	$0.15 /g	$0.15 /g
Type	RX	RX
Active ingredient	HYDROCORTISONE ACETATE	HYDROCORTISONE ACETATE
Manufacturer	Pfizer	Merck
Dosage forms	Tablet, Topical	Injectable, Tablet
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	about 1.5 hours
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

cortril hydrocortone

Rating

64/100

70/100

Pharmacy pays

$0.15 /g

Type

Active ingredient

HYDROCORTISONE ACETATE

Manufacturer

Pfizer

Merck

Dosage forms

Tablet, Topical

Injectable, Tablet

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Get cortril

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is better-rated, Cortril or Hydrocortone?

By our independent rating, Hydrocortone scores higher — 3.5 vs 3.2 out of 5 for Cortril. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Cortril or Hydrocortone?

Pharmacies pay about the same to acquire either one — roughly $0.15 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Cortril and Hydrocortone?

Both Cortril and Hydrocortone share the active ingredient Hydrocortisone Acetate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.