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CORTONE vs ZILRETTA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. CORTONE and ZILRETTA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

cortonezilretta

Rating

70/100
70/100

Pharmacy pays

—
—

Type

RX
RX

Active ingredient

CORTISONE ACETATE
TRIAMCINOLONE ACETONIDE

Manufacturer

Merck
Pacira Pharms Inc

Dosage forms

Injectable, Tablet
Kit

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Treats

Adrenal Insufficiency, Asthma, Berylliosis
Adrenal Insufficiency, Hemolytic Anemia, Berylliosis

Frequently asked questions

Which is better-rated, Cortone or Zilretta?

Cortone and Zilretta are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Zilretta?

Cortone contains Cortisone Acetate, while Zilretta contains Triamcinolone Acetonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.