CORTONE vs PREDNISONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. CORTONE and PREDNISONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	PREDNISONE
Rating	70/100	70/100
Pharmacy pays	—	~$1.77 /30
Type	RX	RX
Active ingredient	CORTISONE ACETATE	PREDNISONE
Manufacturer	Merck	Watson Labs
Dosage forms	Injectable, Tablet	Tablet
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	roughly 2 to 4 hours (short)
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Adrenal Insufficiency, Autoimmune Hemolytic Anemia, Asthma

cortone prednisone

Rating

70/100

Pharmacy pays

—

~$1.77 /30

Type

Active ingredient

CORTISONE ACETATE

PREDNISONE

Manufacturer

Merck

Watson Labs

Dosage forms

Injectable, Tablet

Tablet

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

roughly 2 to 4 hours (short)

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Adrenal Insufficiency, Autoimmune Hemolytic Anemia, Asthma

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Frequently asked questions

Which is better-rated, Cortone or Prednisone?

Cortone and Prednisone are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Prednisone?

Cortone contains Cortisone Acetate, while Prednisone contains Prednisone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.