CORTONE vs METHYLPREDNISOLONE ACETATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. CORTONE and METHYLPREDNISOLONE ACETATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	METHYLPREDNISOLONE ACETATE
Rating	70/100	70/100
Pharmacy pays	—	~$30.69 /30
Type	RX	RX
Active ingredient	CORTISONE ACETATE	METHYLPREDNISOLONE ACETATE
Manufacturer	Merck	Amneal
Dosage forms	Injectable, Tablet	Injectable
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Adrenal Insufficiency, Asthma, Berylliosis

cortone methylprednisolone acetate

Rating

70/100

Pharmacy pays

—

~$30.69 /30

Type

Active ingredient

CORTISONE ACETATE

METHYLPREDNISOLONE ACETATE

Manufacturer

Merck

Amneal

Dosage forms

Injectable, Tablet

Injectable

Drug class

Corticosteroid

Boxed warning

None

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Frequently asked questions

Which is better-rated, Cortone or Methylprednisolone Acetate?

Cortone and Methylprednisolone Acetate are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Methylprednisolone Acetate?

Cortone contains Cortisone Acetate, while Methylprednisolone Acetate contains Methylprednisolone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.