CORTONE vs HYDELTRASOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTONE and HYDELTRASOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	HYDELTRASOL
Rating	70/100	70/100
Pharmacy pays	—	$0.60 /mL
Type	RX	RX
Active ingredient	CORTISONE ACETATE	PREDNISOLONE SODIUM PHOSPHATE
Manufacturer	Merck	Merck
Dosage forms	Injectable, Tablet	Topical, Injectable
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	2 to 4 hours
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Adrenal Insufficiency, Hemolytic Anemia, Asthma

cortone hydeltrasol

Rating

70/100

Pharmacy pays

—

$0.60 /mL

Type

Active ingredient

CORTISONE ACETATE

PREDNISOLONE SODIUM PHOSPHATE

Manufacturer

Merck

Dosage forms

Injectable, Tablet

Topical, Injectable

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

2 to 4 hours

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Adrenal Insufficiency, Hemolytic Anemia, Asthma

Frequently asked questions

Which is better-rated, Cortone or Hydeltrasol?

Cortone and Hydeltrasol are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Hydeltrasol?

Cortone contains Cortisone Acetate, while Hydeltrasol contains Prednisolone Sodium Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.