CORTONE vs FML

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTONE and FML are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	FML
Rating	70/100	72/100
Pharmacy pays	—	$12.85 /mL
Type	RX	RX
Active ingredient	CORTISONE ACETATE	FLUOROMETHOLONE
Manufacturer	Merck	Allergan
Dosage forms	Injectable, Tablet	Drops
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Conjunctivitis, Inflammation, Keratitis

cortone fml

Rating

70/100

72/100

Pharmacy pays

—

$12.85 /mL

Type

Active ingredient

CORTISONE ACETATE

FLUOROMETHOLONE

Manufacturer

Merck

Allergan

Dosage forms

Injectable, Tablet

Drops

Drug class

Corticosteroid

Boxed warning

None

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Conjunctivitis, Inflammation, Keratitis

Frequently asked questions

Which is better-rated, Cortone or Fml?

By our independent rating, Fml scores higher — 3.6 vs 3.5 out of 5 for Cortone. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cortone and Fml?

Cortone contains Cortisone Acetate, while Fml contains Fluorometholone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.