CORTONE vs DESONIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTONE and DESONIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	DESONIDE
Rating	70/100	70/100
Pharmacy pays	—	$0.28 /g
Type	RX	RX
Active ingredient	CORTISONE ACETATE	DESONIDE
Manufacturer	Merck	Fougera Pharms
Dosage forms	Injectable, Tablet	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

cortone desonide

Rating

70/100

Pharmacy pays

—

$0.28 /g

Type

Active ingredient

CORTISONE ACETATE

DESONIDE

Manufacturer

Merck

Fougera Pharms

Dosage forms

Injectable, Tablet

Topical

Drug class

Corticosteroid

Boxed warning

None

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

Get desonide

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Frequently asked questions

Which is better-rated, Cortone or Desonide?

Cortone and Desonide are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Desonide?

Cortone contains Cortisone Acetate, while Desonide contains Desonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.