CORTONE vs DECADERM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTONE and DECADERM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	DECADERM
Rating	70/100	70/100
Pharmacy pays	—	$0.24 /mL
Type	RX	RX
Active ingredient	CORTISONE ACETATE	DEXAMETHASONE
Manufacturer	Merck	Merck
Dosage forms	Injectable, Tablet	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 4 hours
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Addison Disease, Brain Edema, Bursitis

cortone decaderm

Rating

70/100

Pharmacy pays

—

$0.24 /mL

Type

Active ingredient

CORTISONE ACETATE

DEXAMETHASONE

Manufacturer

Merck

Dosage forms

Injectable, Tablet

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 4 hours

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Addison Disease, Brain Edema, Bursitis

Frequently asked questions

Which is better-rated, Cortone or Decaderm?

Cortone and Decaderm are tied at 3.5 out of 5 by our independent rating.

What is the difference between Cortone and Decaderm?

Cortone contains Cortisone Acetate, while Decaderm contains Dexamethasone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.