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CORTENEMA vs SOLU-CORTEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CORTENEMA and SOLU-CORTEF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.15 /g
$0.15 /g

Type

RX
RX

Active ingredient

HYDROCORTISONE
HYDROCORTISONE SODIUM SUCCINATE

Dosage forms

Enema
Injectable

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Half-life

about 1.5 hours
about 1.5 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis
Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

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Frequently asked questions

Which is cheaper, Cortenema or Solu-Cortef?

Pharmacies pay about the same to acquire either one — roughly $0.15 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Cortenema and Solu-Cortef?

Cortenema contains Hydrocortisone, while Solu-Cortef contains Hydrocortisone Sodium Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.