CORTENEMA vs OXYLONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTENEMA and OXYLONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTENEMA	OXYLONE
Rating	70/100	New
Pharmacy pays	$0.15 /g	$12.85 /mL
Type	RX	RX
Active ingredient	HYDROCORTISONE	FLUOROMETHOLONE
Manufacturer	Ani Pharms	Pharmacia and Upjohn
Dosage forms	Enema	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	—
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Conjunctivitis, Inflammation, Keratitis

cortenema oxylone

Rating

70/100

New

Pharmacy pays

$0.15 /g

$12.85 /mL

Type

Active ingredient

HYDROCORTISONE

FLUOROMETHOLONE

Manufacturer

Ani Pharms

Pharmacia and Upjohn

Dosage forms

Enema

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

—

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Conjunctivitis, Inflammation, Keratitis

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Frequently asked questions

What is the difference between Cortenema and Oxylone?

Cortenema contains Hydrocortisone, while Oxylone contains Fluorometholone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.