CORTENEMA vs LIDEX-E

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTENEMA and LIDEX-E are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTENEMA	LIDEX-E
Rating	70/100	70/100
Pharmacy pays	$0.15 /g	$0.31 /g
Type	RX	RX
Active ingredient	HYDROCORTISONE	FLUOCINONIDE
Manufacturer	Ani Pharms	Alvogen
Dosage forms	Enema	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	—
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

cortenema lidex-e

Rating

70/100

Pharmacy pays

$0.15 /g

$0.31 /g

Type

Active ingredient

HYDROCORTISONE

FLUOCINONIDE

Manufacturer

Ani Pharms

Alvogen

Dosage forms

Enema

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

—

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

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Frequently asked questions

Which is better-rated, Cortenema or Lidex-E?

Cortenema and Lidex-E are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Cortenema or Lidex-E?

Cortenema costs pharmacies less to acquire — about $0.15 vs $0.31 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cortenema and Lidex-E?

Cortenema contains Hydrocortisone, while Lidex-E contains Fluocinonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.