CORTENEMA vs LIDEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CORTENEMA and LIDEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTENEMA	LIDEX
Rating	70/100	70/100
Pharmacy pays	$0.15 /g	$0.31 /g
Type	RX	RX
Active ingredient	HYDROCORTISONE	FLUOCINONIDE
Manufacturer	Ani Pharms	Alvogen
Dosage forms	Enema	Solution, Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	—
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

cortenema lidex

Rating

70/100

Pharmacy pays

$0.15 /g

$0.31 /g

Type

Active ingredient

HYDROCORTISONE

FLUOCINONIDE

Manufacturer

Ani Pharms

Alvogen

Dosage forms

Enema

Solution, Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

—

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

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Frequently asked questions

Which is better-rated, Cortenema or Lidex?

Cortenema and Lidex are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Cortenema or Lidex?

Cortenema costs pharmacies less to acquire — about $0.15 vs $0.31 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cortenema and Lidex?

Cortenema contains Hydrocortisone, while Lidex contains Fluocinonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.