CORTENEMA vs DELTA-CORTEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

Possible drug interaction. CORTENEMA and DELTA-CORTEF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTENEMA	DELTA-CORTEF
Rating	70/100	New
Pharmacy pays	$0.15 /g	$0.60 /mL
Type	RX	RX
Active ingredient	HYDROCORTISONE	PREDNISOLONE
Manufacturer	Ani Pharms	Pharmacia and Upjohn
Dosage forms	Enema	Tablet
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	2 to 4 hours
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Adrenal Insufficiency, Hemolytic Anemia, Asthma

cortenema delta-cortef

Rating

70/100

New

Pharmacy pays

$0.15 /g

$0.60 /mL

Type

Active ingredient

HYDROCORTISONE

PREDNISOLONE

Manufacturer

Ani Pharms

Pharmacia and Upjohn

Dosage forms

Enema

Tablet

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

2 to 4 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Adrenal Insufficiency, Hemolytic Anemia, Asthma

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Frequently asked questions

What is the difference between Cortenema and Delta-Cortef?

Cortenema contains Hydrocortisone, while Delta-Cortef contains Prednisolone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.