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CORTENEMA vs CYCLOCORT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTENEMA and CYCLOCORT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

$0.15 /g
$4.91 /g

Type

RX
RX

Active ingredient

HYDROCORTISONE
AMCINONIDE

Manufacturer

Dosage forms

Enema
Topical

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Half-life

about 1.5 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis
Dermatitis, Facial Dermatoses, Foot Dermatoses

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Frequently asked questions

Which is better-rated, Cortenema or Cyclocort?

By our independent rating, Cyclocort scores higher — 3.6 vs 3.5 out of 5 for Cortenema. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Cortenema or Cyclocort?

Cortenema costs pharmacies less to acquire — about $0.15 vs $4.91 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cortenema and Cyclocort?

Cortenema contains Hydrocortisone, while Cyclocort contains Amcinonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.