CORTEF ACETATE vs DECADERM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. CORTEF ACETATE and DECADERM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTEF ACETATE	DECADERM
Rating	New	72/100
Pharmacy pays	$0.14 /g	$0.24 /mL
Type	RX	RX
Active ingredient	HYDROCORTISONE ACETATE	DEXAMETHASONE
Manufacturer	Pharmacia and Upjohn	Merck
Dosage forms	Topical, Injectable	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	about 4 hours
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Addison Disease, Brain Edema, Bursitis

cortef acetate decaderm

Rating

New

72/100

Pharmacy pays

$0.14 /g

$0.24 /mL

Type

Active ingredient

HYDROCORTISONE ACETATE

DEXAMETHASONE

Manufacturer

Pharmacia and Upjohn

Merck

Dosage forms

Topical, Injectable

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

about 4 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Addison Disease, Brain Edema, Bursitis

Frequently asked questions

What is the difference between Cortef Acetate and Decaderm?

Cortef Acetate contains Hydrocortisone Acetate, while Decaderm contains Dexamethasone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.