CORT-DOME vs SERNIVO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CORT-DOME and SERNIVO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORT-DOME	SERNIVO
Rating	New	72/100
Pharmacy pays	$0.15 /g	—
Type	RX	RX
Active ingredient	HYDROCORTISONE	BETAMETHASONE DIPROPIONATE
Manufacturer	Bayer Pharms	Primus Pharms
Dosage forms	Topical	Spray/Inhaler
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	—
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Atopic Dermatitis, Facial Dermatoses, Foot Dermatoses

cort-dome sernivo

Rating

New

72/100

Pharmacy pays

$0.15 /g

—

Type

Active ingredient

HYDROCORTISONE

BETAMETHASONE DIPROPIONATE

Manufacturer

Bayer Pharms

Primus Pharms

Dosage forms

Topical

Spray/Inhaler

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

—

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Atopic Dermatitis, Facial Dermatoses, Foot Dermatoses

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Frequently asked questions

What is the difference between Cort-Dome and Sernivo?

Cort-Dome contains Hydrocortisone, while Sernivo contains Betamethasone Dipropionate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.