CORT-DOME vs DECADRON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. CORT-DOME and DECADRON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORT-DOME	DECADRON
Rating	New	72/100
Pharmacy pays	$0.14 /g	$0.24 /mL
Type	RX	RX
Active ingredient	HYDROCORTISONE	DEXAMETHASONE
Manufacturer	Bayer Pharms	Merck
Dosage forms	Topical	Tablet
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	about 1.5 hours	about 4 hours
Treats	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis	Addison Disease, Brain Edema, Bursitis

cort-dome decadron

Rating

New

72/100

Pharmacy pays

$0.14 /g

$0.24 /mL

Type

Active ingredient

HYDROCORTISONE

DEXAMETHASONE

Manufacturer

Bayer Pharms

Merck

Dosage forms

Topical

Tablet

Drug class

Corticosteroid

Boxed warning

None

Half-life

about 1.5 hours

about 4 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Addison Disease, Brain Edema, Bursitis

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Frequently asked questions

What is the difference between Cort-Dome and Decadron?

Cort-Dome contains Hydrocortisone, while Decadron contains Dexamethasone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.