CONCERTA vs LISDEXAMFETAMINE DIMESYLATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. CONCERTA and LISDEXAMFETAMINE DIMESYLATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CONCERTA	LISDEXAMFETAMINE DIMESYLATE
Rating	70/100	70/100
Pharmacy pays	~$18.94 /30	—
Type	RX	RX
Active ingredient	METHYLPHENIDATE HYDROCHLORIDE	LISDEXAMFETAMINE DIMESYLATE
Manufacturer	Janssen Pharms	Ascent Pharms Inc
Dosage forms	Tablet, extended release	Capsule, Tablet, chewable
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	Boxed warning
Half-life	about 2.7 hours	less than 1 hour (parent drug)
Treats	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy	Attention Deficit Disorder with Hyperactivity, Binge Drinking

concerta lisdexamfetamine dimesylate

Rating

70/100

Pharmacy pays

~$18.94 /30

—

Type

Active ingredient

METHYLPHENIDATE HYDROCHLORIDE

LISDEXAMFETAMINE DIMESYLATE

Manufacturer

Janssen Pharms

Ascent Pharms Inc

Dosage forms

Tablet, extended release

Capsule, Tablet, chewable

Drug class

Central Nervous System Stimulant

Boxed warning

Half-life

about 2.7 hours

less than 1 hour (parent drug)

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Attention Deficit Disorder with Hyperactivity, Binge Drinking

Frequently asked questions

Which is better-rated, Concerta or Lisdexamfetamine Dimesylate?

Concerta and Lisdexamfetamine Dimesylate are tied at 3.5 out of 5 by our independent rating.

What is the difference between Concerta and Lisdexamfetamine Dimesylate?

Concerta contains Methylphenidate Hydrochloride, while Lisdexamfetamine Dimesylate contains Lisdexamfetamine Dimesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.