COMPAZINE vs TRILAFON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. COMPAZINE and TRILAFON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COMPAZINE	TRILAFON
Rating	70/100	New
Pharmacy pays	~$5.06 /30	~$5.68 /30
Type	RX	RX
Active ingredient	PROCHLORPERAZINE MALEATE	PERPHENAZINE
Manufacturer	Glaxosmithkline	Schering
Dosage forms	Capsule, extended release, Tablet, Suppository	Tablet
Drug class	Phenothiazine	Phenothiazine
Boxed warning	None	None
Treats	Anxiety Disorders, Dementia, Nausea	Tourette Syndrome, Huntington Disease, Nausea

compazine trilafon

Rating

70/100

New

Pharmacy pays

~$5.06 /30

~$5.68 /30

Type

Active ingredient

PROCHLORPERAZINE MALEATE

PERPHENAZINE

Manufacturer

Glaxosmithkline

Schering

Dosage forms

Capsule, extended release, Tablet, Suppository

Tablet

Drug class

Phenothiazine

Boxed warning

None

Treats

Anxiety Disorders, Dementia, Nausea

Tourette Syndrome, Huntington Disease, Nausea

Frequently asked questions

Which is cheaper, Compazine or Trilafon?

Compazine costs pharmacies less to acquire — about $5.06 vs $5.68 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Compazine and Trilafon?

Compazine contains Prochlorperazine Maleate, while Trilafon contains Perphenazine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.