COMPAZINE vs THIORIDAZINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. COMPAZINE and THIORIDAZINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COMPAZINE	THIORIDAZINE HYDROCHLORIDE
Rating	70/100	70/100
Pharmacy pays	~$5.22 /30	~$22.23 /30
Type	RX	RX
Active ingredient	PROCHLORPERAZINE MALEATE	THIORIDAZINE HYDROCHLORIDE
Manufacturer	Glaxosmithkline	West Ward
Dosage forms	Capsule, extended release, Tablet, Suppository	Tablet
Drug class	Phenothiazine	Phenothiazine
Boxed warning	None	None
Treats	Anxiety Disorders, Dementia, Nausea	Psychotic Disorders, Schizophrenia

compazine thioridazine hydrochloride

Rating

70/100

Pharmacy pays

~$5.22 /30

~$22.23 /30

Type

Active ingredient

PROCHLORPERAZINE MALEATE

THIORIDAZINE HYDROCHLORIDE

Manufacturer

Glaxosmithkline

West Ward

Dosage forms

Capsule, extended release, Tablet, Suppository

Tablet

Drug class

Phenothiazine

Boxed warning

None

Treats

Anxiety Disorders, Dementia, Nausea

Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is better-rated, Compazine or Thioridazine Hydrochloride?

Compazine and Thioridazine Hydrochloride are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Compazine or Thioridazine Hydrochloride?

Compazine costs pharmacies less to acquire — about $5.22 vs $22.23 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Compazine and Thioridazine Hydrochloride?

Compazine contains Prochlorperazine Maleate, while Thioridazine Hydrochloride contains Thioridazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.