COMETRIQ vs SIROLIMUS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. COMETRIQ and SIROLIMUS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COMETRIQ	SIROLIMUS
Rating	New	66/100
Pharmacy pays	—	~$48.61 /30
Type	RX	RX
Active ingredient	CABOZANTINIB S-MALATE	SIROLIMUS
Manufacturer	Exelixis	Apotex
Dosage forms	Capsule, Kit	Solution
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	Boxed warning
Treats	Renal Cell Carcinoma	Lymphangioleiomyomatosis, Perivascular Epithelioid Cell Neoplasms

cometriq sirolimus

Rating

New

66/100

Pharmacy pays

—

~$48.61 /30

Type

Active ingredient

CABOZANTINIB S-MALATE

SIROLIMUS

Manufacturer

Exelixis

Apotex

Dosage forms

Capsule, Kit

Solution

Drug class

Kinase Inhibitor

Boxed warning

None

Boxed warning

Treats

Renal Cell Carcinoma

Lymphangioleiomyomatosis, Perivascular Epithelioid Cell Neoplasms

Frequently asked questions

What is the difference between Cometriq and Sirolimus?

Cometriq contains Cabozantinib S-Malate, while Sirolimus contains Sirolimus — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.