COMETRIQ vs KOSELUGO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. COMETRIQ and KOSELUGO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COMETRIQ	KOSELUGO
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	CABOZANTINIB S-MALATE	SELUMETINIB SULFATE
Manufacturer	Exelixis	Astrazeneca
Dosage forms	Capsule, Kit	Capsule, Powder
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Renal Cell Carcinoma	Neurofibromatosis 1

cometriq koselugo

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

CABOZANTINIB S-MALATE

SELUMETINIB SULFATE

Manufacturer

Exelixis

Astrazeneca

Dosage forms

Capsule, Kit

Capsule, Powder

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Renal Cell Carcinoma

Neurofibromatosis 1

Frequently asked questions

What is the difference between Cometriq and Koselugo?

Cometriq contains Cabozantinib S-Malate, while Koselugo contains Selumetinib Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.