COMETRIQ vs GLEEVEC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. COMETRIQ and GLEEVEC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COMETRIQ	GLEEVEC
Rating	New	70/100
Pharmacy pays	—	~$25.80 /30
Type	RX	RX
Active ingredient	CABOZANTINIB S-MALATE	IMATINIB MESYLATE
Manufacturer	Exelixis	Novartis
Dosage forms	Capsule, Kit	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Renal Cell Carcinoma	Lymphoid Leukemia, Myeloid Leukemia, Hypereosinophilic Syndrome

cometriq gleevec

Rating

New

70/100

Pharmacy pays

—

~$25.80 /30

Type

Active ingredient

CABOZANTINIB S-MALATE

IMATINIB MESYLATE

Manufacturer

Exelixis

Novartis

Dosage forms

Capsule, Kit

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Renal Cell Carcinoma

Lymphoid Leukemia, Myeloid Leukemia, Hypereosinophilic Syndrome

Frequently asked questions

What is the difference between Cometriq and Gleevec?

Cometriq contains Cabozantinib S-Malate, while Gleevec contains Imatinib Mesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.