COLUMVI vs ZYNLONTA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. COLUMVI and ZYNLONTA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLUMVI	ZYNLONTA
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	GLOFITAMAB-GXBM	LONCASTUXIMAB TESIRINE-LPYL
Manufacturer	Genentech Inc	Adc Therapeutics Sa
Dosage forms	Solution	Injectable
Drug class	—	—
Boxed warning	Boxed warning	None
Treats	Diffuse Large B-Cell Lymphoma	Diffuse Large B-Cell Lymphoma

columvi zynlonta

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

GLOFITAMAB-GXBM

LONCASTUXIMAB TESIRINE-LPYL

Manufacturer

Genentech Inc

Adc Therapeutics Sa

Dosage forms

Solution

Injectable

Drug class

—

Boxed warning

None

Treats

Diffuse Large B-Cell Lymphoma

Frequently asked questions

What is the difference between Columvi and Zynlonta?

Columvi contains Glofitamab-Gxbm, while Zynlonta contains Loncastuximab Tesirine-Lpyl — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.