COLUMVI vs EPKINLY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. COLUMVI and EPKINLY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLUMVI	EPKINLY
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	GLOFITAMAB-GXBM	EPCORITAMAB-BYSP
Manufacturer	Genentech Inc	Genmab US, Inc.
Dosage forms	Solution	Injectable
Drug class	—	—
Boxed warning	Boxed warning	Boxed warning
Treats	Diffuse Large B-Cell Lymphoma	Diffuse Large B-Cell Lymphoma

columvi epkinly

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

GLOFITAMAB-GXBM

EPCORITAMAB-BYSP

Manufacturer

Genentech Inc

Genmab US, Inc.

Dosage forms

Solution

Injectable

Drug class

—

Boxed warning

Treats

Diffuse Large B-Cell Lymphoma

Frequently asked questions

What is the difference between Columvi and Epkinly?

Columvi contains Glofitamab-Gxbm, while Epkinly contains Epcoritamab-Bysp — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.