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COLESTIPOL HYDROCHLORIDE vs DIFICID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. COLESTIPOL HYDROCHLORIDE and DIFICID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

colestipol hydrochloridedificid

Rating

66/100
72/100

Pharmacy pays

~$20.09 /30
~$4759.74 /30

Type

RX
RX

Active ingredient

COLESTIPOL HYDROCHLORIDE
FIDAXOMICIN

Manufacturer

Zydus Pharms USA Inc
Cubist Pharms LLC

Dosage forms

Suspension, Tablet
Powder

Drug class

Bile Acid Sequestrant
Macrolide Antibacterial

Boxed warning

None
None

Treats

Coronary Artery Disease, Diarrhea, Pseudomembranous Enterocolitis
Pseudomembranous Enterocolitis

Frequently asked questions

Which is better-rated, Colestipol Hydrochloride or Dificid?

By our independent rating, Dificid scores higher — 3.6 vs 3.3 out of 5 for Colestipol Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colestipol Hydrochloride or Dificid?

Colestipol Hydrochloride costs pharmacies less to acquire — about $20.09 vs $4759.74 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colestipol Hydrochloride and Dificid?

Colestipol Hydrochloride contains Colestipol Hydrochloride, while Dificid contains Fidaxomicin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.