COLAZAL vs TUZISTRA XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. COLAZAL and TUZISTRA XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	TUZISTRA XR
Rating	74/100	72/100
Pharmacy pays	~$11.02 /30	—
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	CHLORPHENIRAMINE POLISTIREX AND CODEINE POLISTIREX
Manufacturer	Valeant Pharm Intl	Tris Pharma Inc
Dosage forms	Capsule	Suspension, extended release
Drug class	Aminosalicylate	—
Boxed warning	None	None
Treats	Ulcerative Colitis	—

colazal tuzistra xr

Rating

74/100

72/100

Pharmacy pays

~$11.02 /30

—

Type

Active ingredient

BALSALAZIDE DISODIUM

CHLORPHENIRAMINE POLISTIREX AND CODEINE POLISTIREX

Manufacturer

Valeant Pharm Intl

Tris Pharma Inc

Dosage forms

Capsule

Suspension, extended release

Drug class

Aminosalicylate

—

Boxed warning

None

Treats

Ulcerative Colitis

—

Frequently asked questions

Which is better-rated, Colazal or Tuzistra XR?

By our independent rating, Colazal scores higher — 3.7 vs 3.6 out of 5 for Tuzistra XR. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Colazal and Tuzistra XR?

Colazal contains Balsalazide Disodium, while Tuzistra XR contains Chlorpheniramine Polistirex and Codeine Polistirex — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.