COLAZAL vs TRANDATE HCT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. COLAZAL and TRANDATE HCT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	TRANDATE HCT
Rating	74/100	72/100
Pharmacy pays	~$11.02 /30	~$0.91 /30
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	HYDROCHLOROTHIAZIDE AND LABETALOL HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Glaxosmithkline
Dosage forms	Capsule	Tablet
Drug class	Aminosalicylate	—
Boxed warning	None	None
Half-life	—	about 6 to 15 hours (the label reports a range, not a single number)
Treats	Ulcerative Colitis	—

colazal trandate hct

Rating

74/100

72/100

Pharmacy pays

~$11.02 /30

~$0.91 /30

Type

Active ingredient

BALSALAZIDE DISODIUM

HYDROCHLOROTHIAZIDE AND LABETALOL HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Glaxosmithkline

Dosage forms

Capsule

Tablet

Drug class

Aminosalicylate

—

Boxed warning

None

Half-life

—

about 6 to 15 hours (the label reports a range, not a single number)

Treats

Ulcerative Colitis

—

Frequently asked questions

Which is better-rated, Colazal or Trandate Hct?

By our independent rating, Colazal scores higher — 3.7 vs 3.6 out of 5 for Trandate Hct. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colazal or Trandate Hct?

Trandate Hct costs pharmacies less to acquire — about $0.91 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Trandate Hct?

Colazal contains Balsalazide Disodium, while Trandate Hct contains Hydrochlorothiazide and Labetalol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.