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COLAZAL vs PYLERA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. COLAZAL and PYLERA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
New

Pharmacy pays

~$11.02 /30
—

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
BISMUTH SUBCITRATE POTASSIUM AND METRONIDAZOLE AND TETRACYCLINE HYDROCHLORIDE

Dosage forms

Capsule
Capsule

Drug class

Aminosalicylate
—

Boxed warning

Half-life

—
about 8 hours

Treats

Ulcerative Colitis
—

Frequently asked questions

What is the difference between Colazal and Pylera?

Colazal contains Balsalazide Disodium, while Pylera contains Bismuth Subcitrate Potassium and Metronidazole and Tetracycline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.