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COLAZAL vs PERCODAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. COLAZAL and PERCODAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
New

Pharmacy pays

~$11.02 /30
~$0.78 /30

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
ASPIRIN AND OXYCODONE HYDROCHLORIDE AND OXYCODONE TEREPHTHALATE

Dosage forms

Capsule
Tablet

Drug class

Aminosalicylate
—

Boxed warning

None
None

Half-life

—
about 3.5 to 4 hours

Treats

Ulcerative Colitis
—

Frequently asked questions

Which is cheaper, Colazal or Percodan?

Percodan costs pharmacies less to acquire — about $0.78 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Percodan?

Colazal contains Balsalazide Disodium, while Percodan contains Aspirin and Oxycodone Hydrochloride and Oxycodone Terephthalate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.