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COLAZAL vs LOMOTIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. COLAZAL and LOMOTIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
52/100

Pharmacy pays

~$11.02 /30
$6.87 /mL

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
ATROPINE SULFATE AND DIPHENOXYLATE HYDROCHLORIDE

Dosage forms

Capsule
Tablet

Drug class

Aminosalicylate
—

Boxed warning

None
None

Treats

Ulcerative Colitis
—

Frequently asked questions

Which is better-rated, Colazal or Lomotil?

By our independent rating, Colazal scores higher — 3.7 vs 2.6 out of 5 for Lomotil. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Colazal and Lomotil?

Colazal contains Balsalazide Disodium, while Lomotil contains Atropine Sulfate and Diphenoxylate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.