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COLAZAL vs FOSAMAX PLUS D

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. COLAZAL and FOSAMAX PLUS D are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
72/100

Pharmacy pays

~$11.02 /30
~$7.71 /30

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
ALENDRONATE SODIUM AND CHOLECALCIFEROL

Dosage forms

Capsule
Tablet

Drug class

Aminosalicylate
—

Boxed warning

None
None

Treats

Ulcerative Colitis
—

Frequently asked questions

Which is better-rated, Colazal or Fosamax Plus D?

By our independent rating, Colazal scores higher — 3.7 vs 3.6 out of 5 for Fosamax Plus D. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colazal or Fosamax Plus D?

Fosamax Plus D costs pharmacies less to acquire — about $7.71 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Fosamax Plus D?

Colazal contains Balsalazide Disodium, while Fosamax Plus D contains Alendronate Sodium and Cholecalciferol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.