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COLAZAL vs FIORINAL W/CODEINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. COLAZAL and FIORINAL W/CODEINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

colazalfiorinal w/codeine

Rating

74/100
72/100

Pharmacy pays

~$11.02 /30
~$0.78 /30

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
ASPIRIN AND BUTALBITAL AND CAFFEINE AND CODEINE PHOSPHATE

Manufacturer

Valeant Pharm Intl
Allergan

Dosage forms

Capsule
Capsule

Drug class

Aminosalicylate
—

Boxed warning

None
None

Half-life

—
about 20 minutes (the label also states 0.33 hours) for aspirin itself

Treats

Ulcerative Colitis
—

Frequently asked questions

Which is better-rated, Colazal or Fiorinal W/Codeine?

By our independent rating, Colazal scores higher — 3.7 vs 3.6 out of 5 for Fiorinal W/Codeine. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colazal or Fiorinal W/Codeine?

Fiorinal W/Codeine costs pharmacies less to acquire — about $0.78 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Fiorinal W/Codeine?

Colazal contains Balsalazide Disodium, while Fiorinal W/Codeine contains Aspirin and Butalbital and Caffeine and Codeine Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.