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COLAZAL vs EPANOVA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. COLAZAL and EPANOVA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
70/100

Pharmacy pays

~$11.02 /30
~$5.16 /30

Type

RX
RX

Active ingredient

BALSALAZIDE DISODIUM
OMEGA-3-CARBOXYLIC ACIDS

Dosage forms

Capsule
Capsule

Drug class

Aminosalicylate
—

Boxed warning

None
None

Treats

Ulcerative Colitis
—

Frequently asked questions

Which is better-rated, Colazal or Epanova?

By our independent rating, Colazal scores higher — 3.7 vs 3.5 out of 5 for Epanova. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colazal or Epanova?

Epanova costs pharmacies less to acquire — about $5.16 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Epanova?

Colazal contains Balsalazide Disodium, while Epanova contains Omega-3-Carboxylic Acids — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.