COLAZAL vs ENOVID-E 21

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. COLAZAL and ENOVID-E 21 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	ENOVID-E 21
Rating	74/100	New
Pharmacy pays	~$11.02 /30	—
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	MESTRANOL AND NORETHYNODREL
Manufacturer	Valeant Pharm Intl	Gd Searle LLC
Dosage forms	Capsule	Tablet
Drug class	Aminosalicylate	—
Boxed warning	None	None
Treats	Ulcerative Colitis	—

colazal enovid-e 21

Rating

74/100

New

Pharmacy pays

~$11.02 /30

—

Type

Active ingredient

BALSALAZIDE DISODIUM

MESTRANOL AND NORETHYNODREL

Manufacturer

Valeant Pharm Intl

Gd Searle LLC

Dosage forms

Capsule

Tablet

Drug class

Aminosalicylate

—

Boxed warning

None

Treats

Ulcerative Colitis

—

Frequently asked questions

What is the difference between Colazal and Enovid-E 21?

Colazal contains Balsalazide Disodium, while Enovid-E 21 contains Mestranol and Norethynodrel — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.