COLAZAL vs DEMI-REGROTON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. COLAZAL and DEMI-REGROTON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	DEMI-REGROTON
Rating	74/100	70/100
Pharmacy pays	~$11.02 /30	~$2.67 /30
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	CHLORTHALIDONE AND RESERPINE
Manufacturer	Valeant Pharm Intl	Sanofi Aventis US
Dosage forms	Capsule	Tablet
Drug class	Aminosalicylate	—
Boxed warning	None	None
Half-life	—	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)
Treats	Ulcerative Colitis	—

colazal demi-regroton

Rating

74/100

70/100

Pharmacy pays

~$11.02 /30

~$2.67 /30

Type

Active ingredient

BALSALAZIDE DISODIUM

CHLORTHALIDONE AND RESERPINE

Manufacturer

Valeant Pharm Intl

Sanofi Aventis US

Dosage forms

Capsule

Tablet

Drug class

Aminosalicylate

—

Boxed warning

None

Half-life

—

about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)

Treats

Ulcerative Colitis

—

Frequently asked questions

Which is better-rated, Colazal or Demi-Regroton?

By our independent rating, Colazal scores higher — 3.7 vs 3.5 out of 5 for Demi-Regroton. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Colazal or Demi-Regroton?

Demi-Regroton costs pharmacies less to acquire — about $2.67 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Demi-Regroton?

Colazal contains Balsalazide Disodium, while Demi-Regroton contains Chlorthalidone and Reserpine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.