COLAZAL vs CONTRAVE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. COLAZAL and CONTRAVE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	CONTRAVE
Rating	74/100	New
Pharmacy pays	~$11.02 /30	~$2.51 /30
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	BUPROPION HYDROCHLORIDE AND NALTREXONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Nalpropion
Dosage forms	Capsule	Tablet, extended release
Drug class	Aminosalicylate	—
Boxed warning	None	Boxed warning
Half-life	—	about 21 hours on average (±9 hours)
Treats	Ulcerative Colitis	—

colazal contrave

Rating

74/100

New

Pharmacy pays

~$11.02 /30

~$2.51 /30

Type

Active ingredient

BALSALAZIDE DISODIUM

BUPROPION HYDROCHLORIDE AND NALTREXONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Nalpropion

Dosage forms

Capsule

Tablet, extended release

Drug class

Aminosalicylate

—

Boxed warning

None

Boxed warning

Half-life

—

about 21 hours on average (±9 hours)

Treats

Ulcerative Colitis

—

Frequently asked questions

Which is cheaper, Colazal or Contrave?

Contrave costs pharmacies less to acquire — about $2.51 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Colazal and Contrave?

Colazal contains Balsalazide Disodium, while Contrave contains Bupropion Hydrochloride and Naltrexone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.