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CODIMAL-L.A. 12 vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. CODIMAL-L.A. 12 and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
74/100

Pharmacy pays

—
~$2.89 /30

Type

RX
RX

Active ingredient

CHLORPHENIRAMINE MALEATE AND PSEUDOEPHEDRINE HYDROCHLORIDE
PRIMIDONE

Dosage forms

Capsule, extended release
Tablet

Drug class

—
Anti-Epileptic Agent

Boxed warning

None
None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)
—

Treats

—
Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

What is the difference between Codimal-L.A. 12 and Mysoline?

Codimal-L.A. 12 contains Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.